PEDIATRICS Vol. 65 No. 5 May 1980, pp. 995-999
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Coronal Craniostenosis: Fetal Head Constraint as One Possible Cause

John M. Graham Jr MD1, Richard J. Badura MD1, and David W. Smith MD1

1 Dysmorphology Unit, Child Development and Mental Retardation Center, and the Center for Inherited Diseases, Department of Pediatrics, University of Washington School of Medicine, Seattle

A retrospective study of 11 instances of idiopathic coronal craniostenosis in otherwise normal children revealed that early lightening, prolonged moderate to severe pelvic discomfort late in pregnancy, and/or an abnormal fetal lie were unusual gestational features indicative of intrauterine constraint for eight of these patients. The impression of unusual constraint in utero was futher implied by finding associated positional foot deformities in four of these latter eight children. We hypothesize that prolonged constraint of the fetal head may limit anteroposterior growth stretch at the coronal suture and thereby predispose toward early sutural fusion.

Submitted on July 19, 1979
Accepted on August 20, 1979




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