PEDIATRICS Vol. 65 No. 3 March 1980, pp. 605-609
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Childhood Primary Aldosteronism Due to an Adrenal Adenoma: Preoperative Localization by Adrenal Vein Catheterization

Arunabha Ganguly MD1, Jerry Bergstein MD1, Clarence E. Grim MD1, Moo Nahm Yum MD1, and Myron H. Weinberger MD1

1 Departments of Medicine, Pediatrics, and Pathology, Indiana University School of Medicine, Indianapolis

Primary aldosteronism resulting from an adrenal adenoma is rare in children. An 8frac12-year-old girl was found to have hypertension and spontaneous hypokalemia, both detected as incidental findings. Subsequent investigations revealed inappropriately elevated levels of plasma and urinary aldosterone with suppressed plasma renin activity. Adrenal vein blood sampling and venography suggested the presence of left adrenal adenoma which was confirmed at surgical exploration and pathologic examination. All the clinical and biochemical abnormalities were corrected by the adrenalectomy. The differential diagnoses of various types of hyperaldosteronism and/or hypokalemia in such a clinical setting are discussed.

Submitted on September 11, 1978
Accepted on November 17, 1978




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