PEDIATRICS Vol. 65 No. 3 March 1980, pp. 473-476
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Myerberg, D. Z.
Right arrow Articles by Gregory, G. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Myerberg, D. Z.
Right arrow Articles by Gregory, G. A.

Comparison of Noninvasive and Direct Measurements of Intracranial Pressure

D. Z. Myerberg MD1, C. York MD1, E. R. Chaplin MD1, and G. A. Gregory MD1

1 Departments of Pediatrics, Neurology and Anesthesiology, and the Cardiovascular Research Institute, University of California, San Francisco

After creating "fontanelles" in infant rhesus monkeys, we measured intracranial pressure of these monkeys directly with an indwelling cannula and indirectly with a Ladd 1700 sensor. Values obtained with the Ladd sensor placed over the shaven fontanelle closely approximate directly measured pressure in acute experiments in these animals and in human cadavers. Application of the device is simple and application pressure need not always be the same for multiple determinations. The response time is 1.6 cm H20/sec, which is adequate to record changes in intracranial pressure caused by changes in the partial pressure of CO2 in arterial blood.

Submitted on May 16, 1979
Accepted on July 9, 1979