PEDIATRICS Vol. 65 No. 1 January 1980, pp. 74-77
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Paroxysmal Choreoathetosis: Report of Five Cases and Review of the Literature

Morris Kinast MD1, Gerald Erenberg MD1, and A. David Rothner MD1

1 Cleveland Clinic Foundation, Diagnostic Center for Children and Youth, Cleveland

Paroxysmal choreoathetosis is a rare, involuntary movement disorder. Attacks occur spontaneously or may be induced by movement, startle, or anxiety. The movements are tonic, dystonic, or choreoathetotic. Sporadic and, more commonly, familial cases have been reported. Onset occurs most often during childhood, and the course is nonprogressive. Response to anticonvulsant therapy is usually excellent. Five cases of the sporadic form of paroxysmal choreoathetosis are reported. Three of the five patients had attacks after initiation of movements such as rising from a chair. Results of physical examination were normal in four patients. One child had mild hemiatrophy and unilateral hyper-reflexia. Results of laboratory studies, including determinations of serum calcium and ceruloplasmin levels, EEGs, and CAT scans of the head, were normal. The attacks ceased in all patients after treatment with either phenytoin or carbamazepine.

Submitted on January 25, 1979
Accepted on April 4, 1979




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