PEDIATRICS Vol. 65 No. 1 January 1980, pp. 30-34
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Clinical Predictability of Intraventricular Hemorrhage in Preterm Infants

Anthony Lazzara MD1, Peter Ahmann MD1, Francine Dykes MD1, Alfred W. Brann Jr MD1, and James Schwartz MD1

1 Department of Pediatrics, Divisions of Newborn Medicine and Pediatric Neurology, Emory University School of Medicine, Atlanta

Ninety-eight infants of less than 35 weeks' gestation, consecutively admitted to a regional neonatal intensive care unit, were followed prior to computerized tomography (CT) scan for clinical signs of subependymal and/or intraventricular hemorrhage. The presence or absence of intracerebral hemorrhage was confirmed by CT scan in all patients, and the severity of hemorrhage was quantitated as mild, moderate, or marked. Thirty-seven out of 98 infants (38%) demonstrated intracerebral hemorrhage on CT scan; 20 of 37 (54%) were predicted clinically. Clinical predictability was related to severity of hemorrhage as quantitated by CT scan. Clinical signs that were found helpful in predicting subependymal and/ or intraventricular hemorrhage were fall in hematocrit, failure of rise in hematocrit with transfusion of packed red blood cells, tight fontanel, decrease in spontaneous activity, decreased tone, abnormal eye signs, and seizures.

Submitted on February 8, 1979
Accepted on May 11, 1979




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S. J. Isenberg and M. Vazquez
Are the Pupils of Premature Infants Affected by Intraventricular Hemorrhage?
J Child Neurol, October 1, 1994; 9(4): 440 - 442.
[Abstract] [PDF]