PEDIATRICS Vol. 64 No. 6 December 1979, pp. 882-891
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Mixed and Obstructive Sleep Apnea and Near Miss for Sudden Infant Death Syndrome: 2. Comparison of Near Miss and Normal Control Infants by Age

Christian Guilleminault MD1, Ronald Ariagno MD1, Rowena Korobkin MD1, Lynn Nagel PhD1, Roger Baldwin MS1, Susan Coons BA1, and Margaret Owen RN1

1 Sleep Research Center and Division of Pediatrics, Stanford University School of Medicine, Stanford, California

Twenty-nine full-term near miss for sudden infant death syndrome (SIDS) and 30 normal control infants underwent 24-hour polygraphic monitoring. Several types of respiratory events during sleep (eg, central, mixed, and obstructive apnea, periodic breathing) were defined and tabulated. Analysis of these respiratory variables and comparison of groups of near miss and control infants indicated that between 3 weeks and 4frac12 months of age only one variable was consistently different at a statistically significant level: the number of mixed and obstructive apnea 3 seconds during total sleep time. This study also showed an increase in mixed and obstructive respiratory events during sleep at 6 weeks of age in control as well as in near miss infants.

Submitted on December 8, 1978
Accepted on April 11, 1979




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