PEDIATRICS Vol. 64 No. 5 November 1979, pp. 598-600
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Stevenson, D. K.
Right arrow Articles by Johnson, J. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stevenson, D. K.
Right arrow Articles by Johnson, J. D.

Pulmonary Excretion of Carbon Monoxide in the Human Newborn Infant as an Index of Bilirubin Production: III. Measurement of Pulmonary Excretion of Carbon Monoxide After the First Postnatal Week in Premature Infants

David K. Stevenson MD1, Albert L. Bartoletti MD1, Clinton R. Ostrander MS1, and John D. Johnson MD1

1 Department of Pediatrics, Stanford University School of Medicine, Stanford, California

Using a single pass, flow-through system, the excretion rate of endogenously produced carbon monoxide ([unknown]eCO) was measured as an index of bilirubin production in 41 Caucasian infants of various gestational ages after the first postnatal week. Twenty-one were le32 weeks gestation. The mean slope for the 25 premature infants with multiple [unknown]eCO determinations was -0.21 ± 0.11 (SE) µl/kg/hour per day (P < .025, one-tailed). Fifteen premature infants with at least three [unknown]eCO determinations during the first 30 days of life had an average decrease in total CO excreted of 1.33% per day compared to the extrapolated initial value of total CO excretion of 27.0 ± 2.0 (SE) µl/hour, giving a calculated maximum red cell life span of 75 days.

Submitted on January 22, 1979
Accepted on March 12, 1979




This article has been cited by other articles:


Home page
 CLIN PEDIATRHome page
C. H. Meyers, L. K. Kwong, H. J. Vreman, and D. K. Stevenson
The Role of Bilirubin Production in Breast-fed Infants with Elevated Serum Bilirubin Concentrations at 2 Weeks of Life
Clinical Pediatrics, September 1, 1984; 23(9): 480 - 482.
[Abstract] [PDF]