Metabolic Alkalosis in Infants with Cystic Fibrosis
1 Department of Pediatrics, Pediatric Pulmonary Division, University of Miami School of Medicine, Miami, FL 33101
Since submission of the article, "Hypoelectrolytemia and metabolic alkalosis in infants with cystic fibrosis," and, during the first eight months of academic practice, I have diagnosed six cystic fibrosis infants under 1 year of age, four of whom had documented episodes of hypoelectrolytemia and severe metabolic alkalosis. The data are included in the Table.
Cases 1 and 2 had recurrent episodes of metabolic alkalosis before the diagnosis of cystic fibrosis was made. Cases 2 and 4 are black infants, in whom the diagnosis of cystic fibrosis would not have been suspected, had not the association between cystic fibrosis and metabolic alkalosis of infancy been recognized.
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F. Greig, M. J. Schoeneman, S. R. Kandall, and R. J. Bonforte Neonatal Hyponatremic Dehydration as an Initial Presentation of Cystic Fibrosis Clinical Pediatrics, September 1, 1993; 32(9): 548 - 551. [PDF] |
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