PEDIATRICS Vol. 64 No. 3 September 1979, pp. 277-282
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Quantitative Noninvasive Method to Measure Cerebral Blood Flow in Newborn Infants

Fergus A. N. Leahy MRCP, DCH1, Koravangattu Sankaran MD1, Don Cates BSc1, Marilyn MacCallum RN1, and Henrique Rigatto MD1

1 Department of Pediatrics, University of Manitoba, Winnipeg, Manitoba, Canada

We measured cerebral blood flow (CBF) in 32 healthy neonates by venous occlusion plethysmography. Mean CBF was 63 ml/min/100 gm which compared favorably with invasive methods used in older children and adult subjects. We suggest that this is a useful method to quantify CBF in neonates. It may be valuable in assessing sequential changes occurring during asphyxia, intracranial hemorrhage, or during administration of various gas mixtures and drugs such as theophylline.

Submitted on August 21, 1978
Accepted on February 5, 1979