PEDIATRICS Vol. 64 No. 2 August 1979, pp. 257-258
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Infectious Mononucleosis and Encephalitis: Recovery of EB Virus from Spinal Fluid

Crystie C. Halsted MD1 and R. Shihman Chang MD, DSc1

1 Departments of Pediatrics and Medical Microbiology, School of Medicine, University of California, Davis, Davis, California

Epstein-Barr virus (EBV), the accepted cause of infectious mononucleosis (IM), has been associated with a variety of neurologic disorders including encephalitis, aseptic meningitis, transverse myelitis, Guillain-Barré syndrome, and Bell's Palsy.1,2 These neurologic syndromes may occur as the sole manifestation of EBV infection or together with the more typical clinical features of IM. It is unclear whether the central nervous manifestations of EBV result from direct invasion of the central nervous system by EBV or from a more indirect mechanism. This report describes the recovery of EBV from the spinal fluid of an 11-year-old boy with IM and encephalitis.

CASE REPORT




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[Abstract] [PDF]