PEDIATRICS Vol. 64 No. 2 August 1979, pp. 172-175
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wilson, W. G.
Right arrow Articles by Aylsworth, A. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wilson, W. G.
Right arrow Articles by Aylsworth, A. S.

Familial Spontaneous Pneumothorax

William G. Wilson MD1 and Arthur S. Aylsworth MD1

1 Department of Pediatrics, Child Development Institute, and Curriculum in Genetics, University of North Carolina, Chapel Hill

A family is described in which four persons in three generations suffered spontaneous pneumothoraces: a newborn, an infant, an adolescent, and an adult. Review of the literature reveals 61 reports of familial spontaneous pneumothorax in 22 families. The ratio of male to female cases is approximately 1.8. Affected parents and affected children (including affected fathers and sons) are seen in ten families, while affected siblings with unaffected parents are noted in 13 families. Consanguinity has not been reported. Although autosomal dominant inheritance has been suggested as an explanation of familial spontaneous pneumothorax, available pedigree data are not adequate for statistical analysis. Physicians should be aware of the familial occurrence of spontaneous pneumothorax so that members of such families may be appropriately managed when problems arise.

Submitted on October 2, 1978
Accepted on December 28, 1978




This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
R. B. Graham, M. Nolasco, B. Peterlin, and C. K. Garcia
Nonsense Mutations in Folliculin Presenting as Isolated Familial Spontaneous Pneumothorax in Adults
Am. J. Respir. Crit. Care Med., July 1, 2005; 172(1): 39 - 44.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
L. Bense, G. Eklund, and R. Lewander
Hereditary Pulmonary Emphysema
Chest, January 1, 2002; 121(1): 297 - 300.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
P. A. Koivisto and A. Mustonen
Primary Spontaneous Pneumothorax in Two Siblings Suggests Autosomal Recessive Inheritance
Chest, May 1, 2001; 119(5): 1610 - 1612.
[Abstract] [Full Text] [PDF]