PEDIATRICS Vol. 64 No. 2 August 1979, pp. 160-164
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Increased Work of Breathing Associated with Nasal Prongs

Steven L. Goldman MD1, June P. Brady MB, BChir1, and Fe M. Dumpit BS1

1 Children's Hospital of San Francisco and the Cardiovascular Research Institute, University of California, San Francisco

To see if continuous distending pressure (CDP) given by nasal prongs increases work of breathing, we measured the mechanics of breathing, minute ventilation, and blood gases in nine infants with both nasal prong and face mask CDP. Minute ventilation was 16% larger (P < .02), work of breathing was 94% higher (P < .01), and the mean PaO2 was 8 mm Hg lower (P < .03) with the nasal prongs. There was no difference in pH or PaCO2. We speculate that CDP given by nasal prongs may increase the risk of respiratory failure in the premature infant already compromised with hyaline membrane disease.

Submitted on July 25, 1978
Accepted on December 27, 1978




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