PEDIATRICS Vol. 63 No. 5 May 1979, pp. 823-824
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Diet Discontinuation in Phenylketonuria

Malclom Wulliamson PH.D.1, Richard Koch M.D.1, and Stanley Berlow M.D.2

1 Los Angeles
2 Diet Discontinuation Committee University of Wisconsin, Madison, Wisconsin

The Collaborative Study of Children Treated for phenylketonuria (PKU) is being conducted in 15 medical centers throughout the United States.1 In this study, initiated in 1967, 140 PKU children were treated from near birth to 6 years of age. At age 6, with the consent of the parents, each child was randomly assigned to one of two groups, either to continue on a phenylalanine-restricted diet, or to discontinue dietary restrictions and eat a normal diet.