Gastrointestinal Bleeding Due to Oral Dicloxacillin Therapy for Osteomyelitis
1 Olive View Medical Center 7533 Van Nuys Boulevard Van Nuys, CA 91405
Adverse gastrointestinal reactions to oral dicloxacillin are enumerated as hepatotoxicity, nausea, vomiting, epigastric discomfort, flatulence and loose stools.1 The latter has seldom necessitated discontinuing treatment.2 Gastrointestinal bleeding has not been previously described in the literature as an effect of this drug. A case is presented of gastrointestinal bleeding associated with oral dicloxacillin therapy of acute osteomyelitis.
CASE REPORT
A 16-year-old Mexican-American boy awoke with pain in the left forearm on February 27, 1978. There was no history of trauma, illness, allergy, or drug intolerance. Physical examination was entirely negative except for temperature of 38.3 C and exquisite point tenderness of the left distal ulna, without overlying skin changes.




