PEDIATRICS Vol. 63 No. 3 March 1979, pp. 443-450
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Ototoxicity in Neonates Treated With Gentamicin and Kanamycin: Results of a Four-Year Controlled Follow-Up Study

Terese Finitzo-Hieber Ph.D.1, George H. McCracken Jr. M.D.1, Ross J. Roeser Ph.D.1, Delores A. Allen B.S., L.P.T.1, Dale F. Chrane R.N.1, and Jaunita Morrow M.A.1

1 Department of Pediatrics, the University of Texas Health Science Center at Dallas, Southwestern medical School, and the Callier Center for Communication Disorders, the University of Texas at Dallas

This article reports the results of a four-year follow-up study initiated in 1970 on the long-term effects of gentamicin and kanamvcin use in newborn infants. Audiometric, vestibular, and psychometric evaluations were performed on gentamicin-treated, kanamycin-treated, and untreated, matched control infants and children. No substantial sensorineural hearing loss or vestibular dysfunction was identified in these patients that could be attributed to aminoglycoside therapy. Performances on the Illinois Test of Psycholinguistic Abilities, Beery Test of Visual Motor Integration, the Peabody Picture Vocabulary Test, and on fine and gross motor examinations were comparable for the three study groups.

Submitted on June 29, 1978
Accepted on August 10, 1978




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