PEDIATRICS Vol. 63 No. 2 February 1979, pp. 347
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Letter To The Editor

Alan B. Forsythe PH.D.1 and Sheldon M. Wolf M.D.2

1 Department of Biomathematics, University of California at Los Angeles
2 Department of Neurology, Southern California Permanente Medical Center, Los Angeles

In a follow-up article,1 we divided the children into two groups for the purpose of analysis. In the first group were children with a single, brief, generalized initial febrile seizure and no history of prenatal, perinatal, or postnatal abnormalities that might suggest the possibility of brain damage. In the second group were those children with such birth abnormalities, and/or a severe initial febrile convulsion, and/or abnormal results of neurological examination.

In the first group, the 36-month recurrence rates were 5% for those randomly assigned to continuous phenobarbital therapy and 34% for those receiving intermittent or no phenobarbital therapy (P > .001).