PEDIATRICS Vol. 63 No. 2 February 1979, pp. 344-345
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Respiratory Disease Associated With Gastroesophageal Reflux

Dennis L. Christie M.D.1

1 The Mason Clinic, 1100 Ninth Avenue Seattl, WA 98111

Several recent reports have emphasized the association between gastroesophageal reflux with tracheobronchial aspiration and recurrent episodes of bronchitis, asthma, pneumonitis, bronchiolitis, apnea, and even aborted sudden infant death syndrome.1-4 The majority of these papers have stressed the fact that infants and children with recurrent pulmonary symptoms, such as wheezing, tachypnea, fever, cough, and chest roentgenographic evidence of pneumonitis or pneumonia, may be aspirating gastric contents into the lungs during periods of recumbency or after feeding.

There has been enthusiasm for an antireflux surgical procedure to stop these suspected repeated episodes of aspiration.5 Investigators have relied on an indirect diagnosis of aspiration by demonstrating abnormalities in esophageal function associated with recurrent respiratory disease.




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K. M. Weesner and A. Rosenthal
Gastroesophageal Reflux in Association with Congenital Heart Disease
Clinical Pediatrics, June 1, 1983; 22(6): 424 - 426.
[Abstract] [PDF]