PEDIATRICS Vol. 63 No. 2 February 1979, pp. 204-206
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Spontaneous Closure of Small Ventricular Septal Defects: Ten-Year Follow-up

Bruce S. Alpert M.D.1, David H. Cook M.A.1, P. Jacob Varghese M.D., M.R.C.P.1, and Richard D. Rowe M.D., F.R.C.P.(C)1

1 Division of Cardiology, Department of Paediatrics, The Hospital for Sick Children, Toronto, and the Department of Pediatrics, The Johns Hopkins Hospital, Baltimore

The natural history of small ventricular septal defect (VSD) was studied in 50 infants for up to 10.5 years. The VSD closed spontaneously in 34 patients. Life-table analysis of the data showed that by 10 years of age, 75% of small VSD will close spontaneously; the figure is higher for defects in the muscular septum (83%).

Submitted on April 17, 1978
Accepted on July 13, 1978




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