PEDIATRICS Vol. 62 No. 6 December 1978, pp. 990-995
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Morrison, J. A.
Right arrow Articles by Glueck, C. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Morrison, J. A.
Right arrow Articles by Glueck, C. J.

Lipids and Lipoproteins in 927 Schoolchildren, Ages 6 to 17 Years

John A. Morrison Ph.D.1, Ido deGroot M.P.H.1, Brenda K. Edwards Ph.D.1, Kathe A. Kelly B.Sc.1, Margot J. Mellies M.D.1, Philip Khoury B.A.1, and Charles J. Glueck M.D.1

1 Lipid Research Clinic and General Clinical Research Center, the Department of Epidemiology and Biostatistics, and the Department of Medicine, University of Cincinnati, College of Medicine

To elucidate associations of age. sex, and race with plasma lipoproteins, and to provide percentile distribution data for pediatric lipoproteins, 927 (684 white, 243 black) fasting schoolchildren, ages 6 to 17 years, were studied. During ages 6 to 11 there were no significant changes in lipids or lipoproteins in any of the sex-, racespecific groups, and no consistent trends were evident. For ages 12 to 17 in both black and white male subjects, mean triglyceride levels were higher (P<.001) and mean high density lipoprotein cholesterol (C-HDL) lower than that for ages 6 to 11 (P<.03). Comparing white female subjects in age groups 6 to 11 and 12 to 17, triglycerides and C-HDL did not differ, but the older children had lower low density lipoprotein cholesterol (C-LDL) (P<.001). There were no significant lipid and lipoprotein differences between older and younger black female subjects. In both racial groups, during ages 6 to 11, females had higher mean triglyceride levels and lower mean C-HDL levels than males, but during ages 12 to 17 there were no significant male-female differences in lipids and lipoproteins. For both ages 6 to 11 and 12 to 17, and for both sexes, black children had higher C-HDL levels and lower triglyceride levels than white children. The percentile levels for lipoproteins should allow the practitioner to accurately assess lipoprotein levels in children and facilitate differentiation, in hypercholesterolemic children, among those whose hypercholesterolemia is primarily accounted for by elevated C-HDL, or by elevated C-LDL, who respectively may be at lower and higher risk for eventual development of coronary heart disease.

Submitted on March 15, 1978
Accepted on May 25, 1978




This article has been cited by other articles:


Home page
 PediatricsHome page
J. A. Morrison, L. A. Friedman, and C. Gray-McGuire
Metabolic Syndrome in Childhood Predicts Adult Cardiovascular Disease 25 Years Later: The Princeton Lipid Research Clinics Follow-up Study
Pediatrics, August 1, 2007; 120(2): 340 - 345.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
L. A. Friedman, J. A. Morrison, S. R. Daniels, W. F. McCarthy, and D. L. Sprecher
Sensitivity and Specificity of Pediatric Lipid Determinations for Adult Lipid Status: Findings From the Princeton Lipid Research Clinics Prevalence Program Follow-up Study
Pediatrics, July 1, 2006; 118(1): 165 - 172.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. R. Srinivasan, L. Myers, and G. S. Berenson
Distribution and Correlates of Non-High-Density Lipoprotein Cholesterol in Children: The Bogalusa Heart Study
Pediatrics, September 1, 2002; 110(3): e29 - 29.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
K. Schulpis and G. A. Karikas
Serum Cholesterol and Triglyceride Distribution in 7767 School-aged Greek Children
Pediatrics, May 1, 1998; 101(5): 861 - 864.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
P. O. Kwiterovich Jr, B. A. Barton, R. P. McMahon, E. Obarzanek, S. Hunsberger, D. Simons-Morton, S. Y. S. Kimm, L. A. Friedman, N. Lasser, A. Robson, et al.
Effects of Diet and Sexual Maturation on Low-Density Lipoprotein Cholesterol During Puberty : The Dietary Intervention Study in Children (DISC)
Circulation, October 21, 1997; 96(8): 2526 - 2533.
[Abstract] [Full Text]