PEDIATRICS Vol. 62 No. 5 November 1978, pp. 733-737
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Dietary Fluoride Supplementation for the Prevention of Caries

Ernest Newbrun D.M.D., Ph.D.1

1 Department of Oral Medicine and Hospital Dentistry and Department of Biochemistry and Biophysics, University of California, San Francisco

Fluoride supplements are effective in preventing dental caries if conscientiously taken on a daily basis from birth until at least 12 to 14 years of age. The optimal dose depends on the child's age and the existing fluoride concentration in the water supply. A dosage schedule is recommended that decreases the dose of fluoride in infancy and that is inversely related to the concentration of fluoride in the drinking water.

Submitted on January 31, 1978
Accepted on April 6, 1978




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E. Newbrun
Current Regulations and Recommendations Concerning Water Fluoridation, Fluoride Supplements, and Topical Fluoride Agents
Journal of Dental Research, May 1, 1992; 71(5): 1255 - 1265.
[Abstract] [PDF]