PEDIATRICS Vol. 61 No. 3 March 1978, pp. 500-501
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Unconvinced by CDP Evidence

David A. Belenky M.D.1, Rosemary J. Orr M.B., B.Ch., D.C.H.2, David E. Woodrum M.D.3, and W. Alan Hodson M.D.3

1 Department of Pediatrics, University of Pittsburgh, School of Medicine; Magee-Womens Hospital, Pittsburgh, PA 15213
2 Departments of Anesthesiology and Pediatrics, Children's Orthopedic Hospital, Seattle, WA 98195
3 Department of Pediatrics, University of Washington School of Medicine Seattle, WA 98195

The commentary by Wung et al. (Pediatrics 58: 793, December 1976) on our controlled trial of continuous distending pressure (CDP) for hyaline membrane disease (Pediatrics 58:800, December 1976) raises some questions which merit further discussion.

The first question is the meaning of a negative result (no significant difference) in a controlled trial. Wung et al. suggest that any conclusion with regard to mortality is unjustified in our study because of an apparent trend toward lower mortality with CDP.