PEDIATRICS Vol. 61 No. 3 March 1978, pp. 433-436
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The Gianotti-Crosti Syndrome

Denise Rubenstein M.B., B.Ch.1, Nancy B. Esterly M.D.1, and David Fretzin M.D.1

1 Division of Dermatology, Department of Medicine, Pritzker School of Medicine, University of Chicago, and the Divisions of Dermatology, Departments of Pediatrics and Medicine, Michael Reese Hospital and Medical Center, Chicago

The Gianotti-Crosti syndrome is an infrequently recognized disorder with distinctive characteristics. The eruption, which lasts for two to eight weeks, consists of large, flat-topped, nonpruritic papules on the face, buttocks, and limbs. Its onset may be preceded by fever and upper respiratory tract symptoms. Associated findings include generalized lymphadenopathy, anicteric hepatitis, and HBs antigenemia. Two children with the syndrome are described to bring this entity to the attention of pediatricians.

Submitted on April 7, 1977
Accepted on April 27, 1977




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