PEDIATRICS Vol. 60 No. 5 November 1977, pp. 761
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Dr. Arnaud Replies

Sara B. Arnaud M.D.1

1 Gastroenterology Unit, Saint Marys Hospital, Mayo Foundation, Rochester, Minnesota 55901

Drs. Giangiacomo and Gleason are quite correct in their criticism that the number of patients with vitamin D deficiency rickets is too small for statistical comparison of the concentration of serum 25-hydroxyvitamin D (25-OH-D) in mild, moderate, and severe rickets. For this reason, we did not attempt this type of statistical comparison (Student's t test). The statistical analysis which supports our conclusion is the calculation of the regression between senim 25-OH-D, ng/ml and the stage of the disease, designated by arbitrary numbers 1, 2, and 3 for mild, moderate, and severe.