PEDIATRICS Vol. 60 No. 2 August 1977, pp. 227-234
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Polyarteritis Nodosa in Older Children

Edward B. Blau M.D.1, Rebecca F. Morris M.D.1, and Eduardo J. Yunis M.D.1

1 Departments of Pediatrics and Pathology of the University of Pittsburgh School of Medicine and the Children's Hospital of Pittsburgh

Polyarteritis in the older child is thought to be a rare disease. This study describes 11 children, 3 to 12 years of age, with polyarteritis seen over a five-year period. Fever, abdominal pain, hypertension, and leukocytosis were found in almost all. Renal disease occurred in eight. Examination of muscle, gut, or kidney tissue was an effective means of diagnosis. The pathological changes were the same as those seen in adults. There seemed to be an association between polyarteritis and group A streptococcal infection. Ten patients had a salutary response to high-dose prednisone administration.

Submitted on August 26, 1976
Accepted on December 14, 1976




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