PEDIATRICS Vol. 6 No. 5 November 1950, pp. 743-752
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ALBUMIN THERAPY IN NEPHROSIS

ENRIQUE GALAN M.D.1, OTTO GARCÍA M.D.1, MANUEL PEREZ ESTABLE M.D.1, ORLANDO GARCÍA FAES M.D.1, ELISEO PRADO M.D.1, and GILBERTO ALFONSO M.D.1

1 The Children's Hospital, Havana.

Twelve nephrotic children were treated with intravenous injections of low-sodium concentrated human plasma albumin. Favorable response, as judged by the decrease in weight and edema and the increase in diuresis, was only seen in five cases.

Lack of therapeutic effect on nephrotic edema was due in the majority of cases to the great urinary loss of injected albumin and to the inability of the kidney to excrete the edema fluid mobilized into the circulation by the osmotic effect of albumin.

Submitted on March 5, 1950