PEDIATRICS Vol. 6 No. 4 October 1950, pp. 644-649
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ABSORPTION OF FAT AND VITAMIN A IN PREMATURE INFANTS

II. Effect of Particle Size on the Absorption of These Substances

SOLEDAD MORALES M.D.1, ARTHUR W. CHUNG M.D.2, J. M. LEWIS M.D.2, ANGELINA MESSINA A.B.2, and L. EMMETT HOLT JR. M.D.2

1 The Department of Pediatrics, New York University College of Medicine, The Children's Medical Service, Bellevue Hospital, and the Pediatric Department of Beth Israel Hospital, New York City., Mead Johnson Fellow in Pediatrics.
2 The Department of Pediatrics, New York University College of Medicine, The Children's Medical Service, Bellevue Hospital, and the Pediatric Department of Beth Israel Hospital, New York City.

Six premature infants were fed butter fat and a vitamin A preparation in an emulsified and in an unemulsified form in order to ascertain whether a reduction in particle size facilitates the absorption of these substances. The results of this investigation indicate that by reducing the particle size of fat and of an oily preparation containing vitamin A to 1 to 2 microns by an homogenizing apparatus the absorption of fat and vitamin A was greatly enhanced. Thus, the particle size of fat and of vitamin A preparations plays an important role in the absorption of these substances in premature infants.

Submitted on February 15, 1950


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