PEDIATRICS Vol. 6 No. 4 October 1950, pp. 593-600
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EFFECT OF PANCREATIN ON PLASMA VITAMIN A CURVES IN THE CELIAC SYNDROME

GORDON E. GIBBS PH.D., M.D.1

1 National Research Council Senior Fellow in Pediatrics

Vitamin A concentrations of the plasma have been determined following administration of halibut liver oil with and without pancreatin in infants and children. Thirty-three patients with cystic fibrosis of the pancreas were so studied. Without pancreatin the vitamin A concentration failed to rise. With pancreatin (in dosage of 0.15 gm./kg.) an average rise in vitamin A occurred approximating 39% of that found in normal control patients. No consistent effect of pancreatin was found in 10 cases of celiac disease.

Submitted on December 26, 1949