PEDIATRICS Vol. 58 No. 5 November 1976, pp. 722-729
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Familial Aggregation of Blood Pressures of Newborn Infants and Their Mothers

Yhu-Hsiung Lee M.D.1, Bernard Rosner Ph.D.1, Jeffrey B. Gould M.D.1, Ernest W. Lowe M.D.1, and Edward H. Kass M.D., Ph.D.1

1 Channing Laboratory and the Departments of Medicine, Medical Microbiology, Pediatrics, and Obstrics and Gynecology, Boston City Hospital, the Departments of Pediatrics, Medicine, and Preventive and Social Medicine, Harvard Medical School, and the Department of Pediatrics and Obstetrics and Gynecology, Boston University School of Medicine, Boston, Massachusetts

The blood pressures and pulse rates of 257 normal full-term infants and their mothers were measured two to four days after birth. Birthweight was correlated with systolic (P = .038), but not with diastolic blood pressure. Infants who were asleep had significantly lower systolic and diastolic blood pressure than infants who were awake (P < .001). Sex, body length, and feedings did not appear to influence infant's blood pressure nor did the anesthesia given to the mothers. Maternal diastolic pressure correlated with infant's diastolic pressure (regression coefficient, .128) (P < .01), whereas for systolic pressure the regression coefficient between maternal and infant pressure was .085 (P = NS). The aggregation between the diastolic blood pressures of infants and mothers was not influenced by birthweight, age of the mother, or medication administered to the mother. The pulse rates of black infants were significantly higher than those of white infants (P < .002). There was correlation between the pulse rates and blood pressures in infants.

Submitted on October 20, 1975
Accepted on February 26, 1976




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