PEDIATRICS Vol. 58 No. 2 August 1976, pp. 259-263
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A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine

G. J. Schwartz M.D.1, G. B. Haycock M.B.1, C. M. Edelmann Jr. M.D.1, and Adrian Spitzer M.D.1

1 Division of Nephrology, Department of Pediatrics, Albert Einstein College of Medicine and Rose F. Kennedy Center, New York, New York

Based on statistical analysis of data in 186 children, a formula was derived which allows accurate estimation of glomerular filtration rate (GFR) from plasma creatinine and body length (GFR (ml/min/1.73 sq m) = 0.55 length (cm)/Pcr (mg/dl). Its application to clearance data in a separate group of 223 children reveals excellent agreement with GFR estimated by the Ccr (r = .935) or Cin (r = .905). This formula should be useful for adjusting dosages of drugs excreted by the kidney and detecting significant changes in renal function.

Submitted on March 18, 1975
Accepted on August 30, 1975




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