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We are writing in regard to the article on anticonvulsant therapy and rickets by Crosley et al.1 Their investigation was apparently stimulated by our reports of the absence of chemical, clinical, and radiographic evidence of rickets in a large series of ambulatory patients receiving antiepileptic drug therapy over a protracted period of time.2-5 These authors utilized a study group consisting of 74 patients attending a pediatric neurologic outpatient clinic and receiving chronic anticonvulsant drug treatment, and a control group composed of 95 children selected from both the pediatric neurology and the general pediatric outpatient populations.