PEDIATRICS Vol. 57 No. 6 June 1976, pp. 897-900
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Crowder, W. L.
Right arrow Articles by Cornblath, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Crowder, W. L.
Right arrow Articles by Cornblath, M.

Neonatal Pancreatic beta-Cell Hyperplasia: Report of a Case With Failure of Diazoxide and Benefit of Early Subtotal Pancreatectomy

Wayne L. Crowder M.D.1, Noel K. Maclaren M.D.1, Ronald L. Gutberlet M.D.1, James L. Frost M.D.1, G. Robert Mason M.D.1, and Marvin Cornblath M.D.1

1 Departments of Pediatrics, Surgery, and Pathology, University of Maryland Hospital, Baltimore

A newborn infant with pancreatic beta-cell hyperplasia had persistent hypoglycemia due to hyperinsulinism. After medical management, including the use of diazoxide and constant glucose infusions had proved ineffective, a subtotal pancreatectomy was curative. Cumulative experience seems to indicate that there should be little delay in performing a subtotal pancreatectomy when aggressive medical management cannot maintain normoglycemia in a neonate.

Submitted on May 27, 1975
Accepted on August 22, 1975