PEDIATRICS Vol. 57 No. 5 May 1976, pp. 696-701
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Needle Biopsy of the Synovium of Children

Jerry C. Jacobs M.D.1, Paul E. Phillips M.D.1, and Austin D. Johnston M.D.1

1 Departments of Pediatrics, Medicine, and Orthopedic Pathology, Columbia University College of Physicians and Surgeons, Babies Hospital, the Children's Medical and Surgical Center, and the Edward Daniels Faulkner Arthritis Clinic, Columbia-Presbyterian Medical Center, New York, New York

While the diagnosis of juvenile rheumatoid arthritis is based on clinical criteria and does not require confirmation by synovial biopsy, biopsy is occasionally desired to exclude other diagnoses. Needle synovial biopsy of the knee may be performed on young children as an office procedure and generally provides adequate tissue for examination. In the author's clinic this procedure has replaced open biopsy of the knee of children.

Submitted on June 9, 1975
Accepted on August 7, 1975




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J. C. Jacobs, S. C. Li, C. Ruzal-Shapiro, H. Kiernan, M. Parisien, and A. Shapiro
Tuberculous Arthritis in Children: Diagnosis by Needle Biopsy of the Synovium
Clinical Pediatrics, June 1, 1994; 33(6): 344 - 348.
[Abstract] [PDF]