1 Division of Human Development, Institute of Nutrition of Central America and Panama, Guatemala
The high prevalence of low-birtheight ( (
2,500 gm) babies in many poor communities is a major public health problem. Studies in humans in situations of acute starvation suggest an effect of maternal nutrition on birth-weight, but less clear results appear under situations of moderate maternal malnutrition. We studied the effects of food supplementation during pregnancy on birthweight in four rural villages of Guatemala, in which two types of supplements were distributed: protein-caloric and caloric.
The caloric supplementation increased the total caloric intake during pregnancy. In both supplements, the amount of calories supplemented during pregnancy showed a consistent nt association with birthweight. In the combined sample the proportion of low-birthweight babies in the high-supplement group (G
20,000 supplemented calories during pregnancy) was 9% compared with 19% in the low-supplement ent gro
(< 20,000 supplemented calories during pregnancy). The relationship between caloric supplementation and birthweight (29 gm of birthweight per 10,000 supplemented ented calories) was basically unchanged after controlling for the maternal home diet, height, head circumference, parity, gestational age, duration of disease during pregnancy, socioeconomic status, and different rates of missing data. Moreover, a similar association was found in consecutive pregnancies of the same mother. We concluded that caloric supplementation during pregnancy produced the observed increase in birthweight.
This article has been cited by other articles:
![]() |
A. D. Stein, M. Wang, M. Ramirez-Zea, R. Flores, R. Grajeda, P. Melgar, U. Ramakrishnan, and R. Martorell Exposure to a Nutrition Supplementation Intervention in Early Childhood and Risk Factors for Cardiovascular Disease in Adulthood: Evidence from Guatemala Am. J. Epidemiol., December 15, 2006; 164(12): 1160 - 1170. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Shaheen, A. de Francisco, S. El Arifeen, E.-C. Ekstrom, and L. A. Persson Effect of prenatal food supplementation on birth weight: an observational study from Bangladesh Am. J. Clinical Nutrition, June 1, 2006; 83(6): 1355 - 1361. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. E. Murphy, R. Smith, W. B. Giles, and V. L. Clifton Endocrine Regulation of Human Fetal Growth: The Role of the Mother, Placenta, and Fetus Endocr. Rev., April 1, 2006; 27(2): 141 - 169. [Abstract] [Full Text] [PDF] |
||||
![]() |
Z. A. Bhutta, G. L. Darmstadt, B. S. Hasan, and R. A. Haws Community-Based Interventions for Improving Perinatal and Neonatal Health Outcomes in Developing Countries: A Review of the Evidence Pediatrics, February 1, 2005; 115(2/S1): 519 - 617. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. M. Catalano, J. P. Kirwan, S. Haugel-de Mouzon, and J. King Gestational Diabetes and Insulin Resistance: Role in Short- and Long-Term Implications for Mother and Fetus J. Nutr., May 1, 2003; 133(5): 1674S - 1683. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. H.D. Fall, C. S. Yajnik, S. Rao, A. A. Davies, N. Brown, and H. J.W. Farrant Micronutrients and Fetal Growth J. Nutr., May 1, 2003; 133(5): 1747S - 1756. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Christian, S. K Khatry, J. Katz, E. K Pradhan, S. C LeClerq, S. R. Shrestha, R. K Adhikari, A. Sommer, and K. P West Jr Effects of alternative maternal micronutrient supplements on low birth weight in rural Nepal: double blind randomised community trial BMJ, March 15, 2003; 326(7389): 571 - 571. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. D. Stein, A. Conlisk, B. Torun, D. G. Schroeder, R. Grajeda, and R. Martorell Cardiovascular Disease Risk Factors Are Related to Adult Adiposity but Not Birth Weight in Young Guatemalan Adults J. Nutr., August 1, 2002; 132(8): 2208 - 2214. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. G Schroeder and R. Martorell Fatness and body mass index from birth to young adulthood in a rural Guatemalan population Am. J. Clinical Nutrition, July 1, 1999; 70 (1): 137S - 144S. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. S. Strauss and W. H. Dietz Low Maternal Weight Gain in the Second or Third Trimester Increases the Risk for Intrauterine Growth Retardation J. Nutr., May 1, 1999; 129(5): 988 - 993. [Abstract] [Full Text] |
||||
![]() |
J Bongaarts Does malnutrition affect fecundity? A summary of evidence Science, May 9, 1980; 208(4444): 564 - 569. [Abstract] [PDF] |
||||
![]() |
B. M. Lester A Synergistic Process Approach to the Study of Prenatal Malnutrition International Journal of Behavioral Development, December 1, 1979; 2(4): 377 - 393. [Abstract] [PDF] |
||||