PEDIATRICS Vol. 56 No. 3 September 1975, pp. 487
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Posture and Salt Intake Affect Study

Joseph Giangiacomo M.D.1

1 Department of Pediatrics, St. Louis University School of Medicine, Cardinal Glennon Memorial Hospital for Children St. Louis, Missouri

The study by Goldberg et al. was performed under conditions which would permit variation of plasma renin. According to their protocol, blood was drawn for renin levels after a 12-hour overnight fast. The dietary sodium was unrestricted. The patients were sitting, but had been ambulatory for several hours and spot-check urine for sodium was obtained within 30 minutes of the blood collection. Renin release is affected by many physiologic and pharmacologic variables; thus, the system is quite labile.