PEDIATRICS Vol. 56 No. 1 July 1975, pp. 41-44
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Chronic Vulvovaginitis in Children Due to Shigella flexneri

Thomas C. Davis M.D.1

1 Department of Pediatrics, DHEW, USPHS, Phoenix Indian Medical Center, Phoenix, Arizona

Although previous reports have implicated Shigella flexneri in resistant or chronic cases of vulvovaginitis in children, no authors have described the clinical findings of this condition. The report presents four cases of persistent vulvovaginitis in prepubertal Indian girls from different reservation communities in Arizona. S. flexneri was isolated in pure culture from the vaginal discharge of each patient. All four cases were characterized by a prolonged vaginitis with a bloody, punilent discharge which responded poorly or not at all to various topical modes of therapy for nonspecific vaginitis. Three cases cleared completely when treated with orally given ampicillin for one week. The striking similarity of these cases suggests that chronic Shigella vulvovaginitis is a recognizable clinical entity and should be considered in the differential diagnosis of persistent vaginitis in children, especially in those from communities where Shigella is endemic.

Submitted on September 30, 1974
Accepted on October 31, 1974




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(Continued from page 145)
Clinical Pediatrics, February 1, 1980; 19(2): 151 - 151.
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