PEDIATRICS Vol. 56 No. 1 July 1975, pp. 123-126
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Levin, S.
Right arrow Articles by Mogilner, B. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Levin, S.
Right arrow Articles by Mogilner, B. M.

T System Immune-Deficiency in Down's Syndrome

Stanley Levin M.B., B.Ch.1, Erga Nir M.Sc.1, and Benjamin M. Mogilner M.D., M.Sc.1

1 Department of Pediatric Research, Kaplan Hospital Rehovot, Israel

Children with Down's syndrome (mongolism) are known to suffer frequent infections, particularly of the respiratory tract. This clinical observation has been confirmed in an epidemiological study in Denmark showing a 50-fold increased incidence of infectious diseases and a 123-fold increase of respiratory infections in mongols as compared to the normal population. In a clinicopathological study of all infants dying in our hospital over a period of ten years, we were impressed by the finding that all 13 cases of mongolism coming to autopsy showed marked lymphocyte depletion of thymus and lymph nodes.




This article has been cited by other articles:


Home page
 NEJMHome page
J. A. Boyce and E. J. Mark
Case 40-1999- A Four-Month-Old Girl with Chronic Cyanosis and Diffuse Pulmonary Infiltrates
N. Engl. J. Med., December 30, 1999; 341(27): 2075 - 2083.
[Full Text] [PDF]