PEDIATRICS Vol. 55 No. 6 June 1975, pp. 861-865
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Myelofibrosis-Myeloid Metaplasia in Childhood

Laurence A. Boxer M.D.1, Bruce M. Camitta M.D.2, William Berenberg M.D.2, and Joseph P. Fanning M.D.1

1 Section on Hematology, Division of Pediatric Hematology and Oncology, Children's Hospital Medical Center and Children's Cancer Research Foundation, and Department of Pediatrics, Harvard Medical School, Boston; and Department of Pathology, Maine Medical Center, Portland
2 Section on Hematology, Division of Pediatric Hematology and Oncology, and Children's Hospital Medical Center and Children's Cancer Research Foundation, and Department of Pediatrics, Harvard Medical School, Boston; and Department of Pathology, Maine Medical Center, Portland

A child with idiopathic myeloid metaplasia is described and her course contrasted with another child having myeloid metaplasia secondary to reticulum cell sarcoma. Despite prior reports the idiopathic form of illness may pursue a relatively indolent course in children. A thorough search should be made for underlying disease when myeloid metaplasia is first diagnosed.

Submitted on March 15, 1974
Accepted on May 21, 1974




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