PEDIATRICS Vol. 55 No. 5 May 1975, pp. 744
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Treatment of Acrodermatitis Enteropathica With Zinc Sulfate

Vazken M. Der Kaloustian M.D.1 and Salim S. Musallam M.D.1

1 Department of Pediatrics, American University of Beirut Beirut, Lebanon

Recently many articles have appeared in Pediatrics1-3 and in the literature4 relating the toxic effects of diiodohydroxyquin (Diodoquin) on the eye. In many instances the medication had been used for the treatment of acrodermatitis enteropathica.3-5

Following the report by Moynahan6 of successful treatment of this condition with the oral administration of zinc sulfate, we treated a 7-year-old boy suffering from acrodermatitis enteropathica with 50 mg of zinc sulfate by mouth, three times daily. The effect of this regimen was dramatic with complete clearing of all the skin lesions, regrowth of normal hair, and arrest of the diarrhea.