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PEDIATRICS Vol. 55 No. 5 May 1975, pp. 738-739
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Treatment of Acrodermatitis Enteropathica With Zinc Sulfate

Alex F. Robertson M.D.1, Juan Sotos M.D.2

1 Department of Pediatrics, Medical College of Georgia Augusta, Georgia 30902 Columbus, Ohio
2 Department of Pediatrics, Ohio State University, School of Medicine, and Columbus Children's Hospital Research Foundation

Dr. Moynahan reported recently the successful treatment of acrodermatitis with zinc sulfate. He informed us that nine of his patients have continued in remission with this treatment and that approximately 20 patients in Scandinavia are responding to this treatment. Since the use of diiodohydroxyquin is sometimes complicated by optic atrophy2 and since zinc treatment has not been reported in this country, we felt it important to describe the successful use of zinc sulfate in two patients and to urge physicians in the United States to try this treatment.

CASE REPORTS

Case 1

C.R. is an 8-year-old white girl diagnosed at 1 month of age as having acrodermatitis and subsequently studied for fatty acid metabolism3 and tryptophan metabolism.4


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C. Eckhert, M. Sloan, Duncan JR, and L. Hurley
Zinc binding: a difference between human and bovine milk
Science, February 25, 1977; 195(4280): 789 - 790.
[Abstract] [PDF]