PEDIATRICS Vol. 55 No. 4 April 1975, pp. 536-538
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by McCann, W. P.
Right arrow Articles by Palmisano, P. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McCann, W. P.
Right arrow Articles by Palmisano, P. A.

Fatal Chloroquine Poisoning in a Child: Experience With Peritoneal Dialysis

William P. McCann M.D.1, Robert Permisohn M.S.1, and P. A. Palmisano M.D.1

1 Departments of Pharmacology and Pediatrics, University of Alabama Medical Center Birmingham, Alabama, and Division of Biochemistry, Walter Reed Army Institute of Research, Walter Reed Army Medical Center Washington, D.C.

Chloroquine overdose is commonly fatal in children.1 We report here such a case in which peritoneal dialysis was tried. Analyses of tissues, serum, urine, and dialysate for chloroquine confirmed the diagnosis and indicated that little of this drug was removed from the body by dialysis.

CASE REPORT

A healthy 28-month-old black boy weighing 17.17 kg was seen holding two 500-mg chloroquine diphosphate (Aralen) tablets from a relative's purse about 3:30 PM one afternoon. One-half hour later he was found unconscious and was brought to the Children's Hospital, arriving at 5 PM apneic and with fixed, dilated pupils. It was stated that breathing stopped just before arrival.