PEDIATRICS Vol. 55 No. 4 April 1975, pp. 479-484
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Nocardiosis in Children: Report of Three Cases and Review of the Literature

Ziad H. Idriss M.D.1, Robert J. Cunningham M.D.1, and Catherine M. Wilfert M.D.1

1 Duke University Medical Center, Department of Pediatrics, Durham, North Carolina

The clinical illnesses observed in three adolescents with Nocardia asteroides infection are described. The organism has been classified as a bacterium and placed in the Actinomycetaceae family. Sulfonamides remain the first choice for chemotherapy but alternative drugs are available and may be essential in successful therapy. Nocardial infections in children indicate the need for evaluation for an underlying immunological deficiency. Nocardia species should be considered as possible causative agents in immunocompromised patients with infection.




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