PEDIATRICS Vol. 55 No. 3 March 1975, pp. 425-427
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Coarctation of the Aorta in Male Cousins With Similar Maternal Environmental Exposure to Insect Repellent and Insecticides

Judith G. Hall M.D.1, John F. McLaughlin M.D.1, and Stanley Stamm M.D.1

1 Children's Orthopedic Hospital, and Departments of Medicine and Pediatrics, University of Washington School of Medicine, Seattle

Two male infants, whose mothers are sisters and whose fathers are unrelated, were born within two weeks of each other. Both infants had coarctation of the aorta. Since both mothers were exposed to an insecticide while on a camping trip in the first trimester of pregnancy, it is unknown whether genetic or environmental factors caused the anomalies. Observations should be made on other patients with congenital heart defects to clarify the etiologic factors.

Submitted on March 6, 1974
Accepted on June 13, 1974