PEDIATRICS Vol. 55 No. 2 February 1975, pp. 300-301
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Sacral Agenesis

Robert L. Lebowitz M.D.1

1 Department of Radiology, The Children's Hospital Medical Center 300 Longwood Avenue Boston, Massachusetts 02115

It is important to recognize the patient with sacral agenesis and associated neurogenic bladder dysfunction before irremediable damage to the urinary tract occurs, as stressed by Thompson, Kirk, and Dale.1 It is also true that this entity is often occult. Thus, any clue to the diagnosis, or statistical association with another clinical problem, is of great help in identifying patients with this malformation, aptly termed "the syndrome of caudal regression" by Duhamel.

Thompson, Kirk, and Dale failed to point out the striking incidence of sacral agenesis in infants of diabetic mothers, first noted in this journal by Rusnak and Driscoll.