1 Departments of Pediatrics and Microbiology Duke University Medical Center Durham, North Carolina
Several causes for false-positive Gram stains of cerebrospinal fluid (CSF) have been recorded previously! We report here an additional cause for misinterpretation of the cerebrospinal fluid Gram stain which is probably related to the use of an open needle to perform the lumbar puncture.
CASE REPORT
The patient was a 1,300-gm black female infant, delivered after a 33-week gestation, who developed mild respiratory distress and hyperbilirubinemia which resolved spontaneously within one week. She received penicillin G and kanamycin for her first five days of life because of apnea and bradycardia, but blood, urine, CSF, and a culture of the tracheal aspirate obtained prior to therapy were all negative for bacteria.