PEDIATRICS Vol. 54 No. 3 September 1974, pp. 268-270
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Mucocutaneous lymph node syndrome (MLNS): A disease widespread in Japan which demands our attention

George H. Fetterman M.D.1 and Yoshie Hashida M.D.1

1 Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania 15213

In 1967 Kawasaki of Tokyo1 described 50 cases of a seemingly self-limited disease syndrome of infants and young children, which he designated as mucocutaneous lymph node syndrome (MLNS). The patients ranged in age from 2 months to 9 years, more than half being under 2 years of age. The cases had come to Kawasaki's attention over a six-year period from 1961 through 1966. The condition was somewhat reminiscent of the Stevens-Johnson syndrome, but was less awesome since all patients recovered. Some resemblance of MLNS to scarlet fever was also noted, but the author was confident that MLNS was different from and could be differentiated from both scarlet fever and the Stevens-Johnson syndrome.