PEDIATRICS Vol. 54 No. 1 July 1974, pp. 5-14
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pildes, R. S.
Right arrow Articles by Peeva, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pildes, R. S.
Right arrow Articles by Peeva, A.

A Prospective Controlled Study of Neonatal Hypoglycemia

Rosita S. Pildes M.D.1, Marvin Cornblath M.D.1, Irvina Warren M.S.S.W.1, Edward Page-El M.D.1, Salvatore di Menza M.A.1, Doris M. Merritt 1, and Antonia Peeva M.A.1

1 Departments of Pediatrics, Cook County Hospital and The Abraham Lincoln School of Medicine, University of Illinois, Chicago, and the School of Medicine, University of Maryland, Baltimore

A follow-up study was done on the physical growth, neurological and EEG abnormalities and intellectual development of 39 treated hypoglycemic children and 41 matched controls up to 5 to 7 years of age.

Although there were no significant differences in mean height and mean weight at 5 to 7 years of age, mean head circumferences remained smaller in the hypoglycemic groups when compared to that of the controls.

No significant EEG differences were found between the groups but a significant difference in neurologic abnormalities was seen. However, in only two of 30 infants who had repeated neurological examinations and who were at least 4 years old at the time of the last examinations could the neurologic abnormality be attributed solely to hypoglycemia which had been adequately treated. These abnormalities were occasional nonfebrile seizures. In a third infant moderate neurologic abnormalities could be traced to unrecognized and inadequately treated symptomatic hypoglycemia, in a fourth to microcephaly and hypoglycemia, and in one infant spastic quadriplegia was associated with cerebral hemorrhage and hypoglycemia.

Although there were no differences in the mean yearly IQ scores between the groups, a significantly (p < .05) larger number of hypoglycemic children had IQ scores below 86 (13 of 25) than did the controls (six of 27) at 5 to 7 years of age.

Submitted on August 2, 1973
Accepted on February 4, 1974




This article has been cited by other articles:


Home page
 PediatricsHome page
E. W. Y. Tam, E. Widjaja, S. I. Blaser, D. L. MacGregor, P. Satodia, and A. M. Moore
Occipital Lobe Injury and Cortical Visual Outcomes After Neonatal Hypoglycemia
Pediatrics, September 1, 2008; 122(3): 507 - 512.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
N. Boluyt, A. van Kempen, and M. Offringa
Neurodevelopment after neonatal hypoglycemia: a systematic review and design of an optimal future study.
Pediatrics, June 1, 2006; 117(6): 2231 - 2243.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child.Home page
P L P Brand, N L D Molenaar, C Kaaijk, and W S Wierenga
Neurodevelopmental outcome of hypoglycaemia in healthy, large for gestational age, term newborns
Arch. Dis. Child., January 1, 2005; 90(1): 78 - 81.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
M. Cornblath, J. M. Hawdon, A. F. Williams, A. Aynsley-Green, M. P. Ward-Platt, R. Schwartz, and S. C. Kalhan
Controversies Regarding Definition of Neonatal Hypoglycemia: Suggested Operational Thresholds
Pediatrics, May 1, 2000; 105(5): 1141 - 1145.
[Abstract] [Full Text]

Home page
 CLIN PEDIATRHome page
L. P. Halamek and D. K. Stevenson
Neonatal Hypoglycemia, Part II: Pathophysiology and Therapy
Clinical Pediatrics, January 1, 1998; 37(1): 11 - 16.
[Abstract] [PDF]