PEDIATRICS Vol. 54 No. 1 July 1974, pp. 118
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Familial Congenital Duodenal Atresia

Vazken M. Der Kaloustian M.D.1, Michel S. Slim M.D.1, and Henry G. Mishalany M.D.1

1 Departments of Pediatrics and Surgery, American University of Beirut, Beirut, Lebanon

More evidence for the genetic etiology of a form of duodenal atresia has been coming our way since the publication of our report in Pediatrics,1 followed by a Letter to the Editor.2

The original paper and the follow-up letter reported three patients with congenital duodenal atresia in two families closely related. All four parents were first cousins of each other and an autosomal recessive type of inheritance was suggested. The source of the proposed gene for both families was traced to a single individual.