PEDIATRICS Vol. 53 No. 5 May 1974, pp. 692-701
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Liver-Spleen Scanning in Pediatrics

Nancy Rosenfield M.D.1 and S. Treves M.D.1

1 Departments of Radiology, Harvard Medical School and Children's Hospital Medical Center, Boston

Liver-spleen scans on 254 children were reviewed retrospectively with regard to accuracy and yield of the examination. The scan predicted abnormality correctly 95% of the time and normality correctly 86% of the time. Pitfalls in interpretation include the nonspecificity of abnormalities present on the scan, confusion of extrinsic with intrinsic defects, and normal anatomical variations with pathology. The technetium-99m-sulfur colloid scan was found to be most helpful in diagnosing splenic abnormalities, in working up abdominal masses, and in evaluating tumor patients after a baseline scan. It was found least useful in patients with fever of unknown origin, abdominal pain, diffuse liver disease, and most inflammatory conditions. Liver abscesses were not found in febrile, otherwise healthy children. The iodine-131-rose bengal liver scan was found to be useful to differentiate potentially curable lesions (e.g., choledochal cysts) from those not surgically treatable.

Submitted on July 18, 1973
Accepted on November 27, 1973




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P.R. Rosen, E.B. Mewborne, R.I. Macpherson, and M.L. Nusynowitz
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[Abstract] [PDF]