PEDIATRICS Vol. 53 No. 5 May 1974, pp. 683-686
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The Effect of Exchange Transfusion on Serum Ionized Calcium

M. Jeffrey Maisels M.B., B.Ch.1, Ting-Kai Li M.D.1, Joseph T. Piechocki Ph.D.1, and Milton W. Werthman M.D.1

1 Division of Medicine and Biochemistry, Walter Reed Army Institute of Research; Pediatric Service, Walter Reed General Hospital; and Department of Pediatrics, Washington Hospital Center, Washington, D.C.

The effect of exchange transfusion on serum ionized calcium concentration was studied during 27 exchange transfusions on 18 newborn infants. When heparinized blood is used negligible changes in serum calcium ion concentration occur, whereas with acid citrate dextrose (ACD) blood a profound fall in ionized calcium occurs which is not prevented by the infusion of calcium gluconate in the usually recommended amount. Ionized calcium levels could not be correlated with the infant's clinical state during the exchange transfusion.

Submitted on September 18, 1973
Accepted on November 29, 1973




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Adverse Events Associated With Exchange Transfusion in Healthy and Ill Newborns
Pediatrics, May 1, 1997; 99(5): e7 - e7.
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