PEDIATRICS Vol. 53 No. 4 April 1974, pp. 501-504
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Neurological Sequelae of Group B Streptococcal Neonatal Infection

Kenneth A. Horn M.D.1, Robert A. Zimmerman Ph.D.1, James D. Knostman M.D.1, and W. Terrence Meyer M.D.1

1 Fort Collins Laboratories, Ecological Investigations Program, Center for Disease Control, Health Services and Mental Health Administration, Public Health Service, Department of Health, Education, and Welfare

Eighteen survivors from a series of 44 infants with neonatal group B streptococcal infection were examined from eight weeks to four years later for possible long-term neurological sequelae. Of six infants with laboratory-validated group B streptococcal meningitis, one died at 11 months of age as a result of complications of hydrocephalus, and another infant was found to have minor neurological sequelae. Of the remaining 12 infants with documented or probable group B sepsis, two were found to have neurological residua. The combined morbidity and mortality rate in the group of 44 infants was 50% (18 deaths and four sequelae).

Submitted on July 10, 1973
Accepted on September 27, 1973